cees dekker - An Overview
cees dekker - An Overview
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Applying one-molecule optical and AFM imaging and pressure-spectroscopy strategies, we seek out to unravel the mechanistic elements of the structure and dynamics of chromosomes. Our investigate passions incorporate:
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Multicolor imaging in the bacterial nucleoid and cell division proteins with blue, orange, and near-infrared fluorescent proteins
Sculpting nano-electrodes having a transmission electron beam for electrical and geometrical characterization of nanoparticles.
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and 1st ever review in the dynamics DNA supercoils and the invention of supercoil hopping
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of an individual wire bridging two electrodes
What distinguishes biology from chemistry is the fact that these factors collectively make up a dwelling program. The secret of claimed existence, I do think, lies during the interactions, the interplay of Those people molecules. The big dilemma in regards to the origin of life continues to be unanswered. How did we ever evolve from uncomplicated molecules to the really complex programs we see now? We have no idea. I would like to operate on these kinds of huge, open up questions.’
2011, initial in vitro measurements of transport throughout only one biomimetic nuclear pore elaborate; enhancement of multiplexed magnetic tweezers for kilo-molecule experiments; and solved the system of homology recognition in DNA homologous recombination
The rotors harness energy from the nanoscale drinking water and ion flow that may be created by a static chemical or electrochemical prospective gradient within the nanopore, which happen to be recognized by way of a salt gradient or used voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological problems, suggesting approaches to constructing Electricity-transducing motors at nanoscale interfaces.
Bulk-surface coupling identifies the mechanistic link amongst Min-protein styles in vivo As well as in vitro
Tests pseudotopological and nontopological versions for SMC-pushed DNA loop extrusion against roadblock-traversal experiments
Quite a few new phenomena have been discovered, and he and his investigate group established a number one position During this discipline of research. Dekker and his exploration group found out new physics of nanotubes and also explored the feasibility of molecular electronics. In 1998, they were the 1st to construct a transistor dependant on an individual nanotube molecule.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij fulfilled enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege https://www.ceesdekker.net zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent layout in 2005. (nl)